Rodent Toxicology Services

Moving client compounds swiftly into human studies and onto the market

Concord Biosciences Drug Safety Assessment offers a comprehensive panel of safety evaluations and general toxicology services, coupled with extensive experience to support drug development. Our quality of execution and commitment to on–time delivery enables us to deliver superior value to pharmaceutical and biotechnology companies.

Rodent toxicology services

General toxicology

  • Acute to chronic toxicology studies
  • 2 year carcinogenicity studies (alternate option — transgenic mouse)

Routes of administration

  • Oral Gavage
  • Dietary admixture
  • Intravenous
    –Bolus injection
  • Subcutaneous injection
  • Intramuscular injection
  • Dermal application
  • Intraperitoneal injection


  • Pharmacokinetic studies
  • Excretion mass balance
  • Tissue distribution

Safety pharmacology services

  • Core services
    –Repiratory function
       Motor activity
  • Supplemental studies
    –Gastrointestinal tract
    –Renal function

Support services

  • Ophthalmoscopy
  • Histology
    –All standard methods, paraffin and resin blocks, specific staining at request
  • Formulation analysis
    –HPLC methods
    –LC/MS methods
  • Bioanalytical analysis
  • Custom radiochemical synthesis
  • Toxicokinetic/pharmacokinetic modeling